The importance of intramolecular hydrogen bonds on the translocation of the small drug piracetam through a lipid bilayer-Reference-Cited by-同舟云学术

The importance of intramolecular hydrogen bonds on the translocation of the small drug piracetam through a lipid bilayer

Published:2021 Issue:2 Volume:11 Page:899-908
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Coimbra João T. S.¹²³⁴⁵^ORCID,Feghali Ralph¹²³⁴⁵,Ribeiro Rui P.¹²³⁴⁵,Ramos Maria J.¹²³⁴⁵^ORCID,Fernandes Pedro A.¹²³⁴⁵^ORCID

Affiliation:

1. LAQV

2. REQUIMTE

3. Departamento de Química e Bioquímica

4. Faculdade de Ciências

5. Universidade do Porto

Abstract

Using computational strategies and an analogue compound, we explore and measure the impact of intramolecular hydrogen bonds on the translocation of the small drug piracetam, through biological membrane models.

Funder

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D0RA09995C

Reference72 articles.

1. Charting Hydrogen Bond Anisotropy

2. Probing backbone hydrogen bonding in PDZ/ligand interactions by protein amide-to-ester mutations

3. Potential Functions for Hydrogen Bonds in Protein Structure Prediction and Design

4. Contribution of hydrogen bonds to protein stability

5. Mechanistic insights on the reduction of glutathione disulfide by protein disulfide isomerase

Cited by 53 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. In silico study of RNA polymerase inhibitor drugs for Rift Valley fever virus using RdRp protein as the target;Journal of Pharmacy & Pharmacognosy Research;2025-01-01

2. In-vitro antioxidant and antidiabetic effects of Rorippa indica (L.) extract and fractions with molecular docking, dynamics simulation, ADMET, and PASS studies;Journal of Molecular Structure;2024-11

3. Discovery of in silico pharmacokinetic characteristics, drug-likeness, computational and experimental pKa values of selected unnatural fatty acid derivatives;Phosphorus, Sulfur, and Silicon and the Related Elements;2024-08-28

4. First-principle calculations of the electronic, vibrational, and thermodynamic properties of nitrogen-rich salt of 3,6-dinitramino-1,2,4,5-tetrazine [(NH4)2(DNAT)];Journal of Molecular Modeling;2024-08-09

5. <i>Clitoria ternatea</i> Increases Milk Production in Dairy Cows by Inhibiting Dopamine Receptor D2: A Computational Study;Indonesian Journal of Chemistry;2024-08-01