Classic highlights in porphyrin and porphyrinoid total synthesis and biosynthesis

Author:

Senge Mathias O.12345ORCID,Sergeeva Natalia N.1678ORCID,Hale Karl J.910118

Affiliation:

1. School of Chemistry

2. Trinity Biomedical Sciences Institute

3. Trinity College Dublin

4. The University of Dublin

5. Dublin 2

6. University of Leeds

7. LS2 9JT Leeds

8. UK

9. The School of Chemistry & Chemical Engineering

10. The Queen's University Belfast

11. Belfast BT9 5AG

Abstract

The development of porphyrin synthesis is illustrated, using classic and modern-day examples, which attempt to provide insights, including mechanistic ones, into the most used methods for porphyrin ring-construction and selective functionalization.

Funder

H2020 Marie Skłodowska-Curie Actions

Science Foundation Ireland

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Reference256 articles.

1. Tetrapyrroles: the pigments of life

2. L. Milgrom , The Colors of Life , Oxford University Press , Oxford , 1997

3. R. Willstätter and A.Stoll , Untersuchungen über Chlorophyll. Methoden und Ergebnisse , J. Springer , Berlin, Germany , 1913

4. A masterly historical account of some of the early work is given D. A. Lightner , Bilirubin: Jekyll and Hyde Pigment of Life , Springer , Wien , 2013

5. Exercises in molecular gymnastics—bending, stretching and twisting porphyrins

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