Total synthesis, structural revision and biological evaluation of γ-elemene-type sesquiterpenes-Reference-Cited by-同舟云学术

Total synthesis, structural revision and biological evaluation of γ-elemene-type sesquiterpenes

Published:2018 Issue:42 Volume:16 Page:7843-7850
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Yuan Changchun¹²³⁴⁵^ORCID,Zhong Shangyong¹²³⁴⁵,Li Xingyi¹²³⁴⁵,Wang Yanhong¹²³⁴⁵,Xun Miao-Miao¹²³⁴⁵^ORCID,Bai Yunli¹²³⁴⁵,Zhu Kongkai⁶⁷⁸⁵

Affiliation:

1. National Demonstration Center for Experimental Chemical Engineering Comprehensive Education

2. School of Chemical Engineering and Technology

3. North University of China

4. Taiyuan 030000

5. P.R. China

6. School of Biological Science and Technology

7. University of Jinan

8. Jinan 250022

Abstract

Total synthesis, structural revision and biological evaluation on cancer cell proliferation of γ-elemene-type sesquiterpenes was described. Our synthesis features a convergent synthetic strategy using an aldol reaction and a base-promoted cyclization as key steps.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB02005A

Reference73 articles.

1. Marine natural products

2. The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century

3. Natural sesquiterpenoids