Discovery of urinary metabolomic biomarkers for early detection of acute kidney injury

Author:

Won A Jin1234,Kim Siwon5234,Kim Yoon Gyoon1674,Kim Kyu-Bong1674,Choi Wahn Soo89104,Kacew Sam11121314,Kim Kyeong Seok1516174,Jung Jee H.1234,Lee Byung Mu1516174,Kim Suhkmann5234,Kim Hyung Sik1516174

Affiliation:

1. College of Pharmacy

2. Pusan National University

3. Busan

4. Republic of Korea

5. Department of Chemistry and Chemistry Institute for Functional Materials

6. Dankook University

7. Cheonan-si

8. School of Medicine

9. Konkuk University

10. Chungju 380-701

11. McLaughlin Centre for Population Health Risk Assessment

12. University of Ottawa

13. Ottawa

14. Canada

15. School of Pharmacy

16. Sungkyunkwan University

17. Suwon

Abstract

The molecular mechanism underlying the nephrotoxicity of 3-indoxyl sulfate. 3-Indoxyl sulfate accumulated in the blood and kidney of patient with acute kidney injury and then accelerates tubular cell injury.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

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