Icariin attenuates perfluorooctane sulfonate-induced testicular toxicity by alleviating Sertoli cell injury and downregulating the p38MAPK/MMP9 pathway-Reference-Cited by-同舟云学术

Icariin attenuates perfluorooctane sulfonate-induced testicular toxicity by alleviating Sertoli cell injury and downregulating the p38MAPK/MMP9 pathway

Published:2022 Issue:6 Volume:13 Page:3674-3689
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zhang Yan¹²,Wu Xiaoping¹²,Zhu Kaili¹,Liu Shangyu¹,Yang Yuan¹,Yuan Ding¹,Wang Ting³,He Yumin¹^ORCID,Dun Yaoyan¹,Wu Jie⁴,Zhang Changcheng¹²,Zhao Haixia¹²^ORCID

Affiliation:

1. Third-grade Pharmacological Laboratory on Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, China Three Gorges University, Yichang, Hubei, 443002, China

2. Medical College, China Three Gorges University, Yichang, Hubei, 443002, China

3. Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Department of Pharmacy, Wuhan University of Science and Technology, Wuhan, Hubei, 430081, China

4. Material Analysis and Testing Center, China Three Gorges University, Yichang, Hubei, 443002, China

Abstract

Perfluorooctane sulfonate (PFOS) is widely recognized as causing Sertoli cell injury and testicular toxicity in males.

Funder

National Natural Science Foundation of China

Wuhan University of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D1FO04135E