Exploring coumarin potentialities: development of new enzymatic inhibitors based on the 6-methyl-3-carboxamidocoumarin scaffold-Reference-Cited by-同舟云学术

Exploring coumarin potentialities: development of new enzymatic inhibitors based on the 6-methyl-3-carboxamidocoumarin scaffold

Published:2016 Issue:55 Volume:6 Page:49764-49768
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Fonseca A.¹²³⁴⁵,Matos M. J.¹²³⁴⁵,Reis J.¹²³⁴⁵,Duarte Y.⁶⁷⁸⁹,Gutiérrez M.⁶⁷⁸⁹,Santana L.¹⁰¹¹¹²¹³¹⁴,Uriarte E.¹⁰¹¹¹²¹³¹⁴,Borges F.¹²³⁴⁵

Affiliation:

1. CIQUP/Departamento de Química e Bioquímica

2. Faculdade de Ciências

3. Universidade do Porto

4. Porto

5. Portugal

6. Laboratorio de Síntesis Orgánica

7. Instituto de Química de Recursos Naturales Universidad de Talca

8. Talca

9. Chile

10. Departamento de Química Orgánica

11. Faculdade de Farmacia

12. Universidade de Santiago de Compostela

13. Santiago de Compostela

14. Spain

Abstract

Novel 6-methyl-3-carboxamidocoumarins were synthesized by an effective three step synthetic strategy and screened towards MAO, AChE and BuChE enzymes.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA05262B

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