<i>O</i>-Methylation of carboxylic acids with streptozotocin-Reference-Cited by-同舟云学术

O-Methylation of carboxylic acids with streptozotocin

Published:2022 Issue:26 Volume:20 Page:5230-5233
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zeng Li-Yan¹²^ORCID,Liu Yang¹^ORCID,Han Jiakun¹^ORCID,Chen Jinhong¹^ORCID,Liu Shuwen¹^ORCID,Xi Baomin¹^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharma-ceutical Sciences, Southern Medical University, Guangzhou, 510515, China

2. College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China

Abstract

Streptozotocin (STZ), DNA-alkylating agents in clinical, was newly explored as an agent for O-methyl esterification. With STZ, carboxylic acids, sulfonic acids and phosphorous acids were transformed into methyl esters in 4 hours at RT with good yield after simple workup.

Funder

Guangdong Science and Technology Department

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00578F

Reference35 articles.

1. Recent Advances in Methylation: A Guide for Selecting Methylation Reagents

2. Copper-Catalyzed Methyl Esterification Reactions via C–C Bond Cleavage

3. Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Unactivated Methylene C(sp3)–H Bonds with Primary Alkyl Halides

4. Farewell to the HSAB Treatment of Ambident Reactivity

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