Hydration in aqueous osmolyte solutions: the case of TMAO and urea-Reference-Cited by-同舟云学术

Hydration in aqueous osmolyte solutions: the case of TMAO and urea

Published:2020 Issue:20 Volume:22 Page:11614-11624
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Sahle Christoph J.¹²³^ORCID,Schroer Martin A.⁴⁵⁶⁷^ORCID,Niskanen Johannes⁸⁹¹⁰¹¹,Elbers Mirko¹²¹³¹⁴⁷,Jeffries Cy M.⁴⁵⁶⁷^ORCID,Sternemann Christian¹²¹³¹⁴⁷^ORCID

Affiliation:

1. European Synchrotron Radiation Facility

2. 38000 Grenoble

3. France

4. European Molecular Biology Laboratory (EMBL)

5. Hamburg Outstation c/o DESY

6. Hamburg 22607

7. Germany

8. Department of Physics and Astronomy

9. University of Turku

10. FI-20014 Turun Yliopisto

11. Finland

12. Fakultät Physik/DELTA

13. Technische Universität Dortmund

14. 44221 Dortmund

Abstract

X-ray Raman scattering spectroscopy and first principles simulations reveal details of the hydration and hydrogen-bond topology of trimethylamine N-oxide (TMAO) and urea in aqueous solutions.

Funder

Bundesministerium für Bildung und Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CP/C9CP06785J

Reference93 articles.

1. Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses

2. Living with Water Stress: Evolution of Osmolyte Systems

3. Cosolvent Effects on Protein Stability

4. Forcing Thermodynamically Unfolded Proteins to Fold

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