DNA hybridization detection with 100 zM sensitivity using piezoelectric plate sensors with an improved noise-reduction algorithm-Reference-Cited by-同舟云学术

DNA hybridization detection with 100 zM sensitivity using piezoelectric plate sensors with an improved noise-reduction algorithm

Published:2014 Issue:11 Volume:139 Page:2754-2763
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Kirimli Ceyhun E.¹²³,Shih Wei-Heng⁴⁵⁶,Shih Wan Y.⁴⁷⁶

Affiliation:

1. Lakehead University

2. Department of Chemistry

3. Thunder Bay, Canada

4. Drexel University

5. Department of Materials Science and Engineering

6. Philadelphia, USA

7. School of Biomedical Engineering, Science, and Health Systems

Abstract

We have examined real-time,in situhybridization detection of target DNA (tDNA) in a buffer solution and in urine using 8 μm-thick lead magnesium niobate–lead titanate (PMN–PT) piezoelectric plate sensors (PEPSs) with improved 3-mercaptopropyltrimethoxysilane (MPS) insulation and a new multiple-parabola (>50) resonance peak position fitting algorithm.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/AN/C4AN00215F

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1. Point mutations of the N-ras gene in the blood plasma DNA of patients with myelodysplastic syndrome or acute myelogenous leukaemia

2. Assessing the Use of p16INK4a Promoter Gene Methylation in Serum for Detection of Bladder Cancer

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