Investigation of tetrazine reactivity towards C-nucleophiles: pyrazolone-based modification of biomolecules-Reference-Cited by-同舟云学术

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Investigation of tetrazine reactivity towards C-nucleophiles: pyrazolone-based modification of biomolecules

Published:2019 Issue:2 Volume:17 Page:388-396
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Renault Kévin¹²³⁴⁵,Guillou Clément⁶⁷⁸⁹¹⁰,Renard Pierre-Yves¹²³⁴⁵^ORCID,Sabot Cyrille¹²³⁴⁵^ORCID

Affiliation:

1. Normandie Univ

2. CNRS

3. UNIROUEN

4. INSA Rouen

5. COBRA (UMR 6014)

6. PISSARO Proteomics Platform

7. IRIB

8. Normandie University

9. 76000 Rouen

10. France

Abstract

A modified tetrazine ligation strategy based on the use of carbon-nucleophile partners, which leads to a single molecule conjugate, is reported.

Funder

Agence Nationale de la Recherche

Centre National de la Recherche Scientifique

Institut National des Sciences Appliquées Rouen

Labex

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C8OB02108B

Reference32 articles.

1. Kondrat’eva Ligation: Diels–Alder-Based Irreversible Reaction for Bioconjugation

2. Covalent Modification of Biomolecules through Maleimide-Based Labeling Strategies

3. Developments in the Field of Bioorthogonal Bond Forming Reactions—Past and Present Trends

4. Advances in Chemical Protein Modification

5. A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems

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3. Bifunctional Reagents for Formylglycine Conjugation: Pitfalls and Breakthroughs;ChemBioChem;2020-09-18

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