Practical, mild and efficient electrophilic bromination of phenols by a new I(iii)-based reagent: the PIDA

Practical, mild and efficient electrophilic bromination of phenols by a new I(iii)-based reagent: the PIDA–AlBr3system

Published:2018 Issue:32 Volume:8 Page:17806-17812
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Satkar Yuvraj¹²³⁴⁵^ORCID,Ramadoss Velayudham¹²³⁴⁵^ORCID,Nahide Pradip D.¹²³⁴⁵^ORCID,García-Medina Ernesto¹²³⁴⁵,Juárez-Ornelas Kevin A.¹²³⁴⁵,Alonso-Castro Angel J.¹⁶³⁴⁵,Chávez-Rivera Ruben⁷⁸⁹⁵,Jiménez-Halla J. Oscar C.¹²³⁴⁵^ORCID,Solorio-Alvarado César R.¹²³⁴⁵^ORCID

Affiliation:

1. Universidad de Guanajuato

2. Departamento de Química

3. División de Ciencias Naturales y Exactas

4. Guanajuato

5. México

6. Departamento de Farmacia

7. Universidad Michoacana de San Nicolás de Hidalgo

8. Facultad de Químico Farmacobiología

9. Morelia

Abstract

A practical electrophilic bromination procedure for the phenolic core was developed under efficient and very mild reaction conditions. The new I(iii)-based brominating reagentPhIOAcBroperationally easy to prepare by mixing PIDA and AlBr₃was used.

Funder

Consejo Nacional de Ciencia y Tecnología

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA02982B

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