Dynamic metabolic change of cancer cells induced by natural killer cells at the single-cell level studied by label-free mass cytometry-Reference-Cited by-同舟云学术

Dynamic metabolic change of cancer cells induced by natural killer cells at the single-cell level studied by label-free mass cytometry

Published:2022 Issue:6 Volume:13 Page:1641-1647
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Shen Zizheng¹,Zhao Hansen¹,Yao Huan¹,Pan Xingyu¹,Yang Jinlei¹,Zhang Sichun¹^ORCID,Han Guojun²³⁴,Zhang Xinrong¹^ORCID

Affiliation:

1. Department of Chemistry, Tsinghua University, Beijing 100084, China

2. Institute of Medical Technology, Peking University Health Science Center, Beijing, 100191, China

3. Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China

4. Department of Biomedical Engineering, Peking University Health Science Center, Beijing, 100191, P. R. China

Abstract

Label-free mass cytometry is utilized to study the dynamic metabolic change during apoptosis in HepG2 cells induced by NK92 MI cells at the single-cell level. The metabolic heterogeneity of individual HepG2 cells during apoptosis was revealed.

Funder

National Natural Science Foundation of China

Peking University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D1SC06366A

Reference65 articles.

1. Natural killer cells: diversity in search of a niche

2. Multifunctional Natural Killer Cell Engagers Targeting NKp46 Trigger Protective Tumor Immunity

3. Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus

4. Genetic and Environmental Determinants of Human NK Cell Diversity Revealed by Mass Cytometry

5. „Natural” killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype

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