Activation of apoptosis by rationally constructing NIR amphiphilic AIEgens: surmounting the shackle of mitochondrial membrane potential for amplified tumor ablation-Reference-Cited by-同舟云学术

Activation of apoptosis by rationally constructing NIR amphiphilic AIEgens: surmounting the shackle of mitochondrial membrane potential for amplified tumor ablation

Published:2021 Issue:31 Volume:12 Page:10522-10531
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Li Haidong¹²³⁴^ORCID,Lu Yang⁵⁶⁷⁸,Chung Jeewon¹²³⁴,Han Jingjing¹²³⁴^ORCID,Kim Heejeong¹²³⁴^ORCID,Yao Qichao⁵⁶⁷⁸⁹,Kim Gyoungmi¹²³⁴,Wu Xiaofeng¹²³⁴,Long Saran⁵⁶⁷⁸,Peng Xiaojun⁵⁶⁷⁸^ORCID,Yoon Juyoung¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry and Nanoscience

2. Ewha Womans University

3. Seoul 03760

4. Korea

5. State Key Laboratory of Fine Chemicals

6. Dalian University of Technology

7. Dalian 116024

8. P. R. China

9. Ningbo Institute of Dalian University of Technology

Abstract

In this contribution, based on a “step-by-step” molecular design strategy, a novel NIR amphiphilic AIEgen TPA-S-TPP with a triplet lifetime of 11.43 μs and surmounting the shackle of MMP was successfully fabricated for amplified tumor ablation.

Funder

National Natural Science Foundation of China

Ministry of Science, ICT and Future Planning

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC02227J

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