Photocatalysis in a multi-capillary assembly microreactor: toward up-scaling the synthesis of 2H-indazoles as drug scaffolds
Author:
Affiliation:
1. Center of Intelligent Microprocess of Pharmaceutical Synthesis
2. Department of Chemical Engineering
3. Pohang University of Science and Technology (POSTECH)
4. Pohang
5. 37673 Korea
Abstract
Visible-light-promoted direct arylation of 2H-indazoles using phenyldiazonium salt enabled a single-step and fast synthesis (<1 min) of C3 arylated products in high yields (>65%) in an eosin Y immobilized capillary microreactor.
Funder
National Research Foundation of Korea
Publisher
Royal Society of Chemistry (RSC)
Subject
Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2019/RE/C9RE00239A
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