A one-pot synthetic method for the hetero-bifunctionalization of α-cyclodextrin at the secondary hydroxyl side with high clockwise–counterclockwise selectivity-Reference-Cited by-同舟云学术

A one-pot synthetic method for the hetero-bifunctionalization of α-cyclodextrin at the secondary hydroxyl side with high clockwise–counterclockwise selectivity

Published:2017 Issue:19 Volume:15 Page:4077-4080
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Huang Xi¹²³⁴⁵,Yasunaga Shun¹²³⁴,Fukudome Makoto¹²³⁴,Chen Wen-Hua⁵⁶⁷⁸⁹^ORCID,Yuan De-Qi¹²³⁴^ORCID

Affiliation:

1. Faculty of Pharmaceutical Sciences

2. Kobe Gakuin University

3. Kobe 650-8586

4. Japan

5. Guangdong Provincial Key Laboratory of New Drug Screening

6. School of Pharmaceutical Sciences

7. Southern Medical University

8. Guangzhou 510515

9. P. R. China

Abstract

The first one-pot synthetic method has been established to ensure the sequence-selective, highly efficient introduction of two different functionalities into the secondary side of α-cyclodextrin.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB00719A

Reference30 articles.

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3. C. M. Pedersen and M.Bols, Cyclodextrin-based artificial enzymes: synthesis and function, in Organic Synthesis and Molecular Engineering, ed. M. B. Nielsen, Wiley, 2013, ch. 11, pp. 305–332

4. Metal complexes of functionalized cyclodextrins as enzyme models and chiral receptors

5. Complexation Thermodynamics of Cyclodextrins

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