Click chemistry-assisted synthesis of triazolo linked podophyllotoxin conjugates as tubulin polymerization inhibitors-Reference-Cited by-同舟云学术

Click chemistry-assisted synthesis of triazolo linked podophyllotoxin conjugates as tubulin polymerization inhibitors

Published:2017 Issue:9 Volume:8 Page:1817-1823
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Vishnuvardhan M. V. P. S.¹²³⁴,V. Saidi Reddy¹²³⁴,Chandrasekhar Kunta¹²³⁴,Lakshma Nayak V.¹²³⁴,Sayeed Ibrahim Bin¹²³⁴,Alarifi Abdullah⁵⁶⁷⁸⁹,Kamal Ahmed¹²³⁴⁵^ORCID

Affiliation:

1. Medicinal Chemistry and Pharmacology

2. CSIR-Indian Institute of Chemical Technology

3. Hyderabad 500007

4. India

5. Catalytic Chemistry Research Chair

6. Chemistry Department

7. College of Science

8. King Saud University

9. Riyadh 11451

Abstract

A series of new triazolo linked 4β-amidopodophyllotoxin conjugates (9a–l) were synthesized using click chemistry and evaluated for their antitumor activity.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MD/C7MD00273D

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