Diastereo- and enantioselective reductive amination of cycloaliphatic ketones by preformed chiral palladium complexes

Author:

Cabrera Armando1234,Sharma Pankaj1234,Pérez-Flores F. Javier1234,Velasco Luis1234,Arias J. Luis567,Rubio-Pérez Laura1234

Affiliation:

1. Instituto de Química

2. Universidad Nacional Autónoma de México

3. Ciudad Universitaria

4. Coyoacán 04510, México D.F.

5. Facultad de Estudios Superiores Cuautitlán

6. Departamento de Química

7. Cuautitlán Izcalli, Mexico

Abstract

Chiral cycloaliphatic amines were obtained from the direct asymmetric reductive amination of cycloaliphatic ketones using a preformed chiral palladium catalyst.

Publisher

Royal Society of Chemistry (RSC)

Subject

Catalysis

Reference31 articles.

1. Recent Development on Catalytic Reductive Amination and Applications

2. Approaching Highly Enantioselective Reductive Amination

3. A “Second-Generation Process” for the Synthesis of l-Neopentylglycine:  Asymmetric Reductive Amination Using a Recombinant Whole Cell Catalyst

4. R. O. Hutchins and M. K.Hutchins , in Comprehensive Organic Synthesis , ed. B. M. Trost and I. Fleming , Pergamon, Oxford , 1991

5. B. G. Main and H.Tucker , in Medicinal Chemistry , ed. C. R. Genellin and S. M. Roberts , Academic Press , New York , 1993 , p. 187

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