Expanded porphyrins: functional photoacoustic imaging agents that operate in the NIR-II region-Reference-Cited by-同舟云学术

Expanded porphyrins: functional photoacoustic imaging agents that operate in the NIR-II region

Published:2021 Issue:29 Volume:12 Page:9916-9921
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Chen Jingqin¹²³⁴⁵,Sedgwick Adam C.⁶⁷⁸⁹^ORCID,Sen Sajal⁶⁷⁸⁹^ORCID,Ren Yaguang¹²³⁴⁵,Sun Qinchao¹²³⁴⁵,Chau Calvin⁶⁷⁸⁹^ORCID,Arambula Jonathan F.⁶⁷⁸⁹^ORCID,Sarma Tridib⁶⁷⁸⁹^ORCID,Song Liang¹²³⁴⁵^ORCID,Sessler Jonathan L.⁶⁷⁸⁹^ORCID,Liu Chengbo¹²³⁴⁵^ORCID

Affiliation:

1. Research Center for Biomedical Optics and Molecular Imaging

2. Shenzhen Institute of Advanced Technology

3. CAS Key Laboratory of Health Informatics

4. Chinese Academy of Sciences

5. Shenzhen 518055

6. Department of Chemistry

7. University of Texas at Austin

8. Austin

9. USA

Abstract

In this study, two expanded porphyrins, octaphyrin and naphthorosarin were evaluated as potential PA agents. The nanoparticle encapsulation of octaphyrin successfully enabled the visualization of acidic environments and the discrimination between cancerous and healthy tissues.

Funder

Chinese Academy of Sciences

National Natural Science Foundation of China

National Institutes of Health

Welch Foundation

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC01591E