Amyloid β derived switch-peptides as a tool for investigation of early events of aggregation: a combined experimental and theoretical approach-Reference-Cited by-同舟云学术

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Amyloid β derived switch-peptides as a tool for investigation of early events of aggregation: a combined experimental and theoretical approach

Published:2016 Issue:2 Volume:7 Page:311-316
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Paul Ashim¹²³⁴,Sharma Bhanita¹²³⁴,Mondal Tanmay¹²³⁴,Thalluri Kishore¹²³⁴,Paul Sandip¹²³⁴,Mandal Bhubaneswar¹²³⁴

Affiliation:

1. Department of Chemistry

2. Indian Institute of Technology

3. Guwahati

4. India

Abstract

π → π stacking interaction takes place prior to aggregation as the early event of amyloid aggregation of amyloidogenic peptides.

Funder

Department of Biotechnology , Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C5MD00466G

Reference37 articles.

1. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

2. Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

3. Exogenous Induction of Cerebral ß-Amyloidogenesis Is Governed by Agent and Host

4. A century-old debate on protein aggregation and neurodegeneration enters the clinic

5. Mechanistic Studies of Peptide Self-Assembly: Transient α-Helices to Stable β-Sheets

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2. The Role of Binding Site Specificity in the Disaggregation of Aβ₄₂Fibrils through a Synthetic Paratope;2023-08-14

3. Inhibitory action of indanone-carbamate hybrid molecules on the aggregation of Aβ16−22 peptides and their translocation across POPC lipid bilayer;Journal of Molecular Liquids;2023-08

4. Phenylpropanoids on the Inhibition of β-Amyloid Aggregation and the Movement of These Molecules through the POPC Lipid Bilayer;Langmuir;2022-06-10

5. Inhibition of Aβ_16–22 Peptide Aggregation by Small Molecules and Their Permeation through POPC Lipid Bilayer: Insight from Molecular Dynamics Simulation Study;Journal of Chemical Information and Modeling;2022-03-21

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