Atomic resolution map of the soluble amyloid beta assembly toxic surfaces-Reference-Cited by-同舟云学术

Atomic resolution map of the soluble amyloid beta assembly toxic surfaces

Published:2019 Issue:24 Volume:10 Page:6072-6082
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Ahmed Rashik¹²³⁴^ORCID,Akcan Michael¹²³⁴,Khondker Adree⁵²³⁴,Rheinstädter Maikel C.⁵²³⁴^ORCID,Bozelli José C.¹²³⁴,Epand Richard M.¹²³⁴^ORCID,Huynh Vincent⁶²³⁴,Wylie Ryan G.⁶²³⁴^ORCID,Boulton Stephen¹²³⁴,Huang Jinfeng⁶²³⁴,Verschoor Chris P.⁷²³⁴,Melacini Giuseppe¹²³⁴⁶^ORCID

Affiliation:

1. Department of Biochemistry and Biomedical Sciences

2. McMaster University

3. Hamilton

4. Canada

5. Department of Physics and Astronomy

6. Department of Chemistry and Chemical Biology

7. Department of Health Research Methods, Evidence, and Impact (HEI)

Abstract

Atomic resolution map of the soluble amyloid beta assembly (Aβ_n) “toxic surfaces” that facilitate the early pathogenic events in Alzheimer's disease (AD).

Funder

Natural Sciences and Engineering Research Council of Canada

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC01331H

Reference59 articles.

1. The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

2. Alzheimer's Disease: The Amyloid Cascade Hypothesis

3. Three dimensions of the amyloid hypothesis: time, space and 'wingmen'