Anti-ulcerogenic effect of KFP-H008 against ethanol-induced gastric ulcer via p38 MAPK/NF-κB pathway
Author:
Affiliation:
1. State Key Laboratory of Natural Medicines
2. School of Pharmacy
3. China Pharmaceutical University
4. Nanjing 210009
5. PR China
6. School of Basic Medicine and Clinical Pharmacy
Abstract
KFP-H008, a novel potassium-competitive acid blocker developed for the treatment of acid-related diseases, has been reported to inhibit gastric acid secretion effectively, while its effects on gastric ulcer have not been previously explored.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA08879E
Reference36 articles.
1. Semipurified Ethyl Acetate Partition of Methanolic Extract ofMelastoma malabathricumLeaves Exerts Gastroprotective Activity Partly via Its Antioxidant-Antisecretory-Anti-Inflammatory Action and Synergistic Action of Several Flavonoid-Based Compounds
2. The protective activity of Conyza blinii saponin against acute gastric ulcer induced by ethanol
3. Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
4. Anti-Ulcerogenic Properties of Lycium chinense Mill Extracts against Ethanol-Induced Acute Gastric Lesion in Animal Models and Its Active Constituents
5. Effect and mechanism of evodiamine against ethanol-induced gastric ulcer in mice by suppressing Rho/NF-кB pathway
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