Nanosized epiberberine-loaded chitosan-collagen nanocomposites: synthesis and evaluation of their cognitive and AChE inhibition enhancing potential in a scopolamine-induced amnesia rat model

Author:

Bashir Dar Junaid1,Manzoor Saliha1,Siddiqui Mobin Ahsan1,Bashir Masarat2,Nidhi 3,Rastogi Shweta4,Arora Indu5,Samim Mohammed1ORCID

Affiliation:

1. Department of Chemistry, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi-110062, India

2. COTS, Mirgund, SKUAST Kashmir, Shalimar, Jammu and Kashmir-193121, India

3. Centre for Translational and Clinical Research, Jamia Hamdard, New Delhi-110062, India

4. Hansraj College, Delhi University, Delhi 110007, New Delhi, India

5. Shaheed Rajguru College of Applied Sciences for Women, Delhi 110096, New Delhi, India

Abstract

Epiberberine is one of the main constituents of Coptidis Rhizoma and has been found to be active against diseases such as hyperglycemia, hyperlipidemia, and Alzheimer's disease.

Funder

Indian Council of Medical Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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