Trialkylammonium salt degradation: implications for methylation and cross-coupling-Reference-Cited by-同舟云学术

Trialkylammonium salt degradation: implications for methylation and cross-coupling

Published:2021 Issue:20 Volume:12 Page:6949-6963
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Washington Jack B.¹²³⁴⁵,Assante Michele⁶⁷⁸⁵,Yan Chunhui¹²³⁴⁵^ORCID,McKinney David¹²³⁴⁵,Juba Vanessa¹²³⁴⁵,Leach Andrew G.⁹¹⁰¹¹⁵^ORCID,Baillie Sharon E.¹²¹³⁵,Reid Marc¹²³⁴⁵^ORCID

Affiliation:

1. WestCHEM Department of Pure and Applied Chemistry

2. University of Strathclyde

3. Thomas Graham Building

4. Glasgow

5. UK

6. School of Pharmacy and Biomolecular Sciences

7. Liverpool John Moores University

8. Liverpool

9. Division of Pharmacy and Optometry

10. University of Manchester

11. Manchester

12. GlaxoSmithKline

13. Irvine

Abstract

The dual reactivity of N,N,N-trimethylanilinium salts towards arylation and methylation is decoupled in this mechanistic investigation to enable more strategic application of these salts in either reaction class.

Funder

Leverhulme Trust

Engineering and Physical Sciences Research Council

GlaxoSmithKline

AstraZeneca

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC00757B

Reference76 articles.