Regio- and diastereoselectivity of the 1,3-dipolar cycloaddition of α-aryl nitrone with methacrolein. A theoretical investigation-Reference-Cited by-同舟云学术

Regio- and diastereoselectivity of the 1,3-dipolar cycloaddition of α-aryl nitrone with methacrolein. A theoretical investigation

Published:2015 Issue:28 Volume:5 Page:22126-22134
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Benchouk Wafaa¹²³⁴⁵,Mekelleche Sidi Mohamed¹²³⁴⁵

Affiliation:

1. Laboratory of Applied Thermodynamics and Molecular Modelling

2. Department of Chemistry

3. Faculty of Science

4. University of Tlemcen

5. Tlemcen

Abstract

The mechanism, regio- and diastereoselectivity of the 1,3-dipolar cycloaddition of N-iso-propyl,α-(4-trifluoromethyl)-phenyl nitrone with methacrolein yielding the isoxazolidine cycloadduct has been studied at the B3LYP/6-31G(d) level of theory.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C4RA17285J

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2. An efficient approach to enantiomeric isoxazolidinyl analogues of tiazofurin based on nitrone cycloadditions

3. Diastereoselective synthesis of a collection of new homonucleoside mimetics containing pyrrolo[1,2-b]isoxazoline and pyrrolidine rings

4. Truncated Reverse Isoxazolidinyl Nucleosides: A New Class of Allosteric HIV-1 Reverse Transcriptase Inhibitors

5. Total synthesis of (+)-azimic acid, (+)-julifloridine, and proposed structure ofN-methyljulifloridine via cycloaddition of nitrone to a chiral dipolarophile

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