Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A-Reference-Cited by-同舟云学术

Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A

Published:2020 Issue:55 Volume:56 Page:7565-7568
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Ndukwe Ikenna E.¹²³⁴^ORCID,Wang Xiao⁵⁶⁷⁴,Lam Nelson Y. S.⁸⁹¹⁰^ORCID,Ermanis Kristaps⁸⁹¹⁰,Alexander Kelsey L.¹¹¹²¹³⁴¹⁴^ORCID,Bertin Matthew J.¹⁵¹⁶¹⁷⁴^ORCID,Martin Gary E.¹⁴¹⁸¹⁹⁴^ORCID,Muir Garrett¹⁴²⁰²¹²²,Paterson Ian⁸⁹¹⁰^ORCID,Britton Robert¹⁴²⁰²¹²²^ORCID,Goodman Jonathan M.⁸⁹¹⁰^ORCID,Helfrich Eric J. N.²³²⁴²⁵²⁶^ORCID,Piel Jörn²³²⁴²⁵²⁶^ORCID,Gerwick William H.¹¹¹²¹³⁴,Williamson R. Thomas²⁷²⁸²⁹⁴^ORCID

Affiliation:

1. Complex Carbohydrate Research Center

2. University of Georgia

3. Athens

4. USA

5. Analytical Research & Development

6. Merck & Co. Inc

7. Rahway

8. University Chemical Laboratory

9. Cambridge

10. UK

11. Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences

12. University of California

13. San Diego

14. Department of Chemistry

15. Department of Biomedical and Pharmaceutical Sciences

16. University of Rhode Island

17. Kingston

18. Seton Hall University

19. South Orange

20. Simon Fraser University

21. Burnaby

22. Canada

23. Institute of Microbiology

24. Eidgenössische Technische Hochschule (ETH) Zürich

25. Zurich

26. Switzerland

27. Department of Chemistry & Biochemistry

28. University of North Carolina Wilmington

29. Wilmington

Abstract

A combined computational and anisotropic NMR investigation defined likely configuration of phormidolide.

Funder

National Institutes of Health

Leverhulme Trust

Isaac Newton Trust

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/D0CC03055D

Reference40 articles.

1. Structure and Absolute Stereochemistry of Phormidolide, a New Toxic Metabolite from the Marine Cyanobacterium Phormidium sp.

2. Phormidolides B and C, Cytotoxic Agents from the Sea: Enantioselective Synthesis of the Macrocyclic Core

3. Oscillariolide, a novel macrolide from a blue-green alga Oscillatoria sp.

4. Relative stereochemical determination of ?-hydroxycarbonyl compounds (aldol products) utilizing theJ-based configuration analysis method

5. Extension of the J-Based Configuration Analysis to Multiple Conformer Equilibria: An Application to Sapinofuranone A

Cited by 22 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Leptochelins A–C, Cytotoxic Metallophores Produced by Geographically Dispersed Leptothoe Strains of Marine Cyanobacteria;Journal of the American Chemical Society;2024-06-25

2. Neopetrotaurines A–C, Isoquinoline Alkaloids with an Unprecedented Taurine Bridge from the Sponge Neopetrosia sp;Journal of Natural Products;2024-01-31

3. Enzymatic Halogenation of Terminal Alkynes;Journal of the American Chemical Society;2023-08-18

4. Anisotropic NMR data acquisition with a prototype 400 MHz cryogen‐free NMR spectrometer;Magnetic Resonance in Chemistry;2023-08-02

5. Anisotropic One‐dimensional/Two‐dimensionalNMRin Molecular Analysis;Two‐Dimensional (2D) NMR Methods;2023-04-14