Acetylated pelargonidin-3-<i>O</i>-glucoside alleviates hepatocyte lipid deposition through activating the AMPK-mediated lysosome-autophagy pathway and redox state-Reference-Cited by-同舟云学术

Acetylated pelargonidin-3-O-glucoside alleviates hepatocyte lipid deposition through activating the AMPK-mediated lysosome-autophagy pathway and redox state

Published:2024 Issue:13 Volume:15 Page:6929-6942
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Xie Lianghua¹²,Hao Xin²,Xie Jiahong²,Mo Jianling¹,Yuan Changzheng³,Chen Wei¹²^ORCID

Affiliation:

1. Department of Traditional Chinese Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, China

2. Department of Food Science and Nutrition, College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, 310058, China

3. School of Public Health, Zhejiang University School of Medicine, Hangzhou, 310058, China

Abstract

In this study, Ace Pg3G was elucidated to stimulate AMPK-mediated lysosome-autophagy pathway to ameliorate FFAs-induced lipid deposition in hepatocytes.

Funder

National Natural Science Foundation of China

Zhejiang University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D4FO00185K

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