Responsive calcium-derived nanoassemblies induce mitochondrial disorder to promote tumor calcification

Author:

Zhao Yan1,Yu Xinquan2,Kong Weiheng1,Kong Rong-Mei1ORCID,Zhang Ensheng1ORCID,Xia Lian1ORCID,Zhang Jing3,Qu Fengli12ORCID,Tan Weihong2ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, Shandong 273165, China

2. Department of Pathology, Cancer Hospital of Zhejiang Province, Hangzhou Institute of Medicine, Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China

3. School of Chemistry and Chemical Engineering, University of Jinan, Jinan, Shandong 250022, China

Abstract

A dual-path metabolic destruction-assisted therapeutic strategy by sequentially inducing apoptosis and prompting calcification of tumor cells.

Funder

National Key Research and Development Program of China

Changjiang Scholar Program of Chinese Ministry of Education

Qingdao University of Science and Technology

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Taishan Scholar Foundation of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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