Exploring beetroot (Beta vulgaris L.) for diabetes mellitus and Alzheimer's disease dual therapy: in vitro and computational studies

Author:

Ojo Oluwafemi Adeleke12ORCID,Gyebi Gideon Ampoma3ORCID,Ezenabor Emmanuel Henry1,Iyobhebhe Matthew4,Emmanuel Damilola Abigael1,Adelowo Oluwatumininu Adetoro1,Olujinmi Faith Eniola5,Ogunwale Temitope Emmanuel6,Babatunde Dare Ezekiel7,Ogunlakin Akingbolabo Daniel12,Ojo Adebola Busola8ORCID,Adeyemi Oluyomi Stephen12

Affiliation:

1. Biochemistry Programme, Bowen University, Iwo 232102, Nigeria

2. Good Health and Wellbeing Research Clusters (SDG 03) Bowen University, Iwo 232102, Nigeria

3. Natural Products and Structural (Bio-Chem)-Informatics Research Laboratory (NpsBC-RI), Department of Biochemistry, Bingham University, Karu, Nigeria

4. Department of Biochemistry, Landmark University, Omu-Aran, Nigeria

5. Chemistry and Industrial Chemistry Programme, Bowen University, Iwo 232102, Nigeria

6. Agriculture Programme, Bowen University, Iwo 232102, Nigeria

7. Anatomy Programme, Bowen University, Iwo 232102, Nigeria

8. Department of Biochemistry, Ekiti State University, Ado-Ekiti, Nigeria

Abstract

This study explored the flavonoid-rich extract of beetroot (Beta vulgaris L.) for type 2 diabetes mellitus (T2D) and Alzheimer's disease (AD) dual therapy by using in vitro and molecular simulation studies.

Publisher

Royal Society of Chemistry (RSC)

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