Efficient labeling of organic molecules using 13C elemental carbon: universal access to 13C2-labeled synthetic building blocks, polymers and pharmaceuticals-Reference-Cited by-同舟云学术

Efficient labeling of organic molecules using 13C elemental carbon: universal access to 13C2-labeled synthetic building blocks, polymers and pharmaceuticals

Published:2020 Issue:4 Volume:7 Page:638-647
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Ledovskaya Maria S.¹²³⁴^ORCID,Voronin Vladimir V.¹²³⁴,Rodygin Konstantin S.¹²³⁴⁵,Ananikov Valentine P.¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Chemistry

2. Saint Petersburg State University

3. Peterhof

4. Russia

5. N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences

Abstract

Synthetic methodology enabled by ¹³C-elemental carbon is reported. Calcium carbide Ca¹³C₂ was applied to introduce a universal ¹³C₂ unit in the synthesis of labeled alkynes, O,S,N-vinyl derivatives, labeled polymers and ¹³C₂-pyridazine drug core.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/C9QO01357A

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