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Research progress of anticancer drugs targeting CDK12

  • Published:2023 Issue:9 Volume:14 Page:1629-1644
  • ISSN:2632-8682
  • Container-title:RSC Medicinal Chemistry
  • language:en
  • Short-container-title:RSC Med. Chem.

Author:

Yan Zhijia1,Du Yongli1ORCID,Zhang Haibin1,Zheng Yong1,Lv Huiting1,Dong Ning1,He Fang2

Affiliation:

1. School of Chemistry & Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences), 3501 Da Xue Road, Jinan, 250353, China

2. School of Water Conservancy and Environment, University of Jinan, 336 Nanxinzhuang West Road, Jinan, 250022, China

Abstract

Structural optimization progress and future research directions of CDK12 inhibitors.

Funder

Natural Science Foundation of Shandong Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

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