Middle-down approach: a choice to sequence and characterize proteins/proteomes by mass spectrometry-Reference-Cited by-同舟云学术

Middle-down approach: a choice to sequence and characterize proteins/proteomes by mass spectrometry

Published:2019 Issue:1 Volume:9 Page:313-344
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Pandeswari P. Boomathi¹²³⁴,Sabareesh Varatharajan¹²³⁴^ORCID

Affiliation:

1. Advanced Centre for Bio Separation Technology (CBST)

2. Vellore Institute of Technology (VIT)

3. Vellore

4. India

Abstract

Enhanced sequence coverage, better identification of combinatorial co-occurring PTMs and improved detection of proteoforms are key highlights of middle-down approach and hence, this can be a promiscuous approach for protein sequencing and proteomics.

Funder

Council of Scientific and Industrial Research

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C8RA07200K

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