Crosstalk between gut microbiota and host lipid metabolism in a mouse model of alcoholic liver injury by chronic baijiu or ethanol feeding

Author:

Fang Cheng12ORCID,Zhou Qingwu3,Liu Qingyang3,Jia Wei45,Xu Yan12ORCID

Affiliation:

1. Key Laboratory of Industrial Biotechnology of Ministry of Education, Laboratory of Brewing Microbiology and Applied Enzymology, School of Biotechnology, Jiangnan University, Wuxi 214122, China

2. Beijing Advanced Innovation Center for Food Nutrition and Human Health, School of Food and Chemical Engineering, Beijing Technology and Business University, Beijing, China

3. The Center for Solid-state Fermentation Engineering of Anhui Province, Bozhou, China

4. Center for Translational Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai 200233, China

5. School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China

Abstract

This study demonstrates that compounds in baijiu, a traditional Chinese alcoholic beverage, can attenuate the development of ethanol-induced liver injury by regulating the crosstalk between gut microbiota and host lipid metabolism.

Funder

National Natural Science Foundation of China

Beijing Advanced Innovation Center for Food Nutrition and Human Health

Beijing Technology and Business University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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