Tributyltin induces epigenetic changes and decreases the expression of nuclear respiratory factor-1-Reference-Cited by-同舟云学术

Tributyltin induces epigenetic changes and decreases the expression of nuclear respiratory factor-1

Published:2018 Issue:2 Volume:10 Page:337-345
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Hanaoka Saki¹²³⁴,Ishida Keishi¹²³⁴,Tanaka Saki¹²³⁴,Sakamoto Shuichiro¹²³⁴,Okuda Katsuhiro¹²³⁴,Sanoh Seigo¹²³⁴,Ohta Shigeru¹²³⁴,Kotake Yaichiro¹²³⁴^ORCID

Affiliation:

1. Graduate School of Biomedical and Health Sciences

2. Hiroshima University

3. Minami-ku

4. Japan

Abstract

The toxicity of tributyltin, an organotin environmental contaminant, is potentially mediated by epigenetic changes in the nuclear respiratory factor-1 (NRF-1) promoter region, leading to reduced mitochondrial membrane potential.

Funder

Japan Society for the Promotion of Science

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MT/C7MT00290D

Reference48 articles.

1. Environmental levels, toxicity and human exposure to tributyltin (TBT)-contaminated marine environment. A review

2. HIGHLY PERSISTENT BUTYLTINS IN NORTHERN MARINE SEDIMENTS: A LONG-TERM THREAT FOR THE SAGUENAY FJORD (CANADA)

3. Biological activity of organotin compounds—An overview

4. Daily Intakes of THbutyltin and THphenyltin Compounds from Meals

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