On-chip hydrogel arrays individually encapsulating acoustic formed multicellular aggregates for high throughput drug testing-Reference-Cited by-同舟云学术

On-chip hydrogel arrays individually encapsulating acoustic formed multicellular aggregates for high throughput drug testing

Published:2020 Issue:12 Volume:20 Page:2228-2236
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Hu Xuejia¹²³⁴⁵,Zhao Shukun¹²³⁴⁵,Luo Ziyi⁶⁷³⁸⁵,Zuo Yunfeng¹²³⁴⁵,Wang Fang¹²³⁴⁵,Zhu Jiaomeng¹²³⁴⁵,Chen Longfei¹²³⁴⁵,Yang Dongyong⁹¹⁰³¹¹⁵,Zheng Yajing⁹¹⁰³¹¹⁵,Zheng Yujia⁶⁷³⁸⁵,Cheng Yanxiang⁹¹⁰³¹¹⁵,Zhou Fuling⁶⁷³⁸⁵,Yang Yi¹²³⁴⁵^ORCID

Affiliation:

1. School of Physics & Technology

2. Key Laboratory of Artificial Micro/Nano Structure of Ministry of Education

3. Wuhan University

4. Wuhan 430072

5. China

6. Department of Hematology

7. Zhongnan Hospital of Wuhan University

8. Wuhan 430071

9. Department of Obstetrics and Gynecology

10. Renmin Hospital of Wuhan University

11. Wuhan 430060

Abstract

Multicellular aggregates in three-dimensional (3D) environments provide novel solid tumor models that can provide insight into in vivo drug resistance.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Qingdao National Laboratory for Marine Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/LC/D0LC00255K

Reference39 articles.

1. The inhibition of NF-kB activation decreases the resistance of acute myeloid leukemia cells to TRAIL-induced apoptosis in multicellular aggregates