Impact of aliphatic acyl and aromatic thioamide substituents on the anticancer activity of Ru(ii)-p-cymene complexes with acylthiourea ligands—in vitro and in vivo studies-Reference-Cited by-同舟云学术

Impact of aliphatic acyl and aromatic thioamide substituents on the anticancer activity of Ru(ii)-p-cymene complexes with acylthiourea ligands—in vitro and in vivo studies

Published:2021 Issue:44 Volume:50 Page:16311-16325
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Swaminathan Srividya¹,Haribabu Jebiti¹²^ORCID,Mohamed Subarkhan Mohamed Kasim³^ORCID,Gayathri Dasararaju⁴^ORCID,Balakrishnan Nithya¹^ORCID,Bhuvanesh Nattamai⁵,Echeverria Cesar²^ORCID,Karvembu Ramasamy¹^ORCID

Affiliation:

1. Department of Chemistry, National Institute of Technology, Tiruchirappalli 620015, Tamil Nadu, India

2. Facultad de Medicina, Universidad de Atacama, Los Carreras 1579, 1532502 Copiapo, Chile

3. The First Affiliated Hospital, Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, School of Medicine, Zhejiang University, Hangzhou, 310003, PR China

4. Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600025, India

5. Department of Chemistry, Texas A & M University, College Station, Texas 77842, USA

Abstract

Six acylthiourea-based Ru(ii)-p-cymene complexes (P1–P6) were designed to explore the structure–activity relationship of the complexes under the influence of aliphatic chain length and aromatic conjugation on the C- and N-terminals, respectively.

Funder

Science and Engineering Research Board

Fondo Nacional de Desarrollo Científico y Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/DT/D1DT02611A

Reference61 articles.

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