Surface properties modulate protein corona formation and determine cellular uptake and cytotoxicity of silver nanoparticles-Reference-Cited by-同舟云学术

Surface properties modulate protein corona formation and determine cellular uptake and cytotoxicity of silver nanoparticles

Published:2021 Issue:33 Volume:13 Page:14119-14129
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Barbalinardo Marianna¹^ORCID,Bertacchini Jessika²,Bergamini Linda³,Magarò Maria Sara²^ORCID,Ortolani Luca⁴,Sanson Alessandra³,Palumbo Carla²,Cavallini Massimiliano¹^ORCID,Gentili Denis¹^ORCID

Affiliation:

1. Consiglio Nazionale delle Ricerche, Istituto per lo Studio dei Materiali Nanostrutturati (CNR-ISMN), via P. Gobetti 101, 40129 Bologna, Italy

2. Department of Biomedical, Metabolic and Neural Sciences, Section of Human Morphology, University of Modena and Reggio Emilia, Via del Pozzo 71, 41124 Modena, Italy

3. Consiglio Nazionale delle Ricerche, Istituto di Scienza e Tecnologia dei Materiali Ceramici (CNR-ISTEC), via Granarolo 64, 48018 Faenza, Italy

4. Consiglio Nazionale delle Ricerche, Istituto per la Microelettronica e Microsistemi (CNR-IMM), via P. Gobetti 101, 40129 Bologna, Italy

Abstract

The role of the surface properties of nanoparticles in serum protein adsorption, cellular uptake and cytotoxicity is reported. The surface properties of nanoparticles regulate their ability to adsorb proteins and determine their biological outcomes.

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D0NR08259G

Reference55 articles.

1. Nanochemistry and Nanomedicine for Nanoparticle-based Diagnostics and Therapy

2. Functional Nanomaterials for Phototherapies of Cancer

3. Nanomaterials: Applications in Cancer Imaging and Therapy