Synthesis and pharmacological evaluation of novel selective MOR agonist 6β-pyridinyl amidomorphines exhibiting long-lasting antinociception-Reference-Cited by-同舟云学术

Synthesis and pharmacological evaluation of novel selective MOR agonist 6β-pyridinyl amidomorphines exhibiting long-lasting antinociception

Published:2017 Issue:1 Volume:8 Page:152-157
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Urai Ákos¹²³⁴,Váradi András⁵⁶⁷⁸,Szőcs Levente¹²³⁴,Komjáti Balázs⁹¹⁰¹¹⁴,Le Rouzic Valerie⁵⁶⁷⁸,Hunkele Amanda⁵⁶⁷⁸,Pasternak Gavril W.⁵⁶⁷⁸,Majumdar Susruta⁵⁶⁷⁸,Hosztafi Sándor¹²³⁴

Affiliation:

1. Department of Pharmaceutical Chemistry

2. Semmelweis University

3. Budapest H-1092

4. Hungary

5. Molecular Pharmacology and Chemistry Program and Department of Neurology

6. Memorial Sloan Kettering Cancer Center

7. New York

8. USA

9. Department of Organic Chemistry and Technology

10. Budapest University of Technology and Economics

11. Budapest 1111

Abstract

The synthesized novel 6β-pyridinyl amidomorphines exhibit long-lasting antinociception.

Funder

National Institute on Drug Abuse

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MD/C6MD00450D

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