Bioorthogonal prodrug activation driven by a strain-promoted 1,3-dipolar cycloaddition
Author:
Affiliation:
1. School of Pharmacy
2. University of Otago
3. Dunedin
4. New Zealand
Abstract
Bioorthogonal prodrug activation controlled by the reaction of a trans-cyclooctene with an azide-functionalized prodrug is presented.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/SC/C4SC02574A
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