ZrMOF nanoparticles as quenchers to conjugate DNA aptamers for target-induced bioimaging and photodynamic therapy

Author:

Liu Yuan12345,Hou Weijia678910ORCID,Xia Lian678910,Cui Cheng12345,Wan Shuo678910,Jiang Ying12345,Yang Yu678910,Wu Qiong678910,Qiu Liping12345,Tan Weihong12345ORCID

Affiliation:

1. Molecular Science and Biomedicine Laboratory (MBL)

2. State Key Laboratory of Chemo/Bio-Sensing and Chemometrics

3. College of Biology

4. College of Chemistry and Chemical Engineering

5. Hunan University

6. Department of Chemistry and Department of Physiology and Functional Genomics

7. Center for Research at the Bio/Nano Inter-face

8. Health Cancer Center

9. UF Genetics Institute

10. McKnight Brain Institute

Abstract

Aptamer conjugated porphyrinic metal–organic framework (MOF) achieved target-induced bioimaging and photodynamic therapy.

Funder

National Institutes of Health

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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