Optogenetic Rac1 engineered from membrane lipid-binding RGS-LOV for inducible lamellipodia formation-Reference-Cited by-同舟云学术

Optogenetic Rac1 engineered from membrane lipid-binding RGS-LOV for inducible lamellipodia formation

Author:

Berlew Erin E.¹²³⁴^ORCID,Kuznetsov Ivan A.¹²³⁴^ORCID,Yamada Keisuke¹²³⁴,Bugaj Lukasz J.¹²³⁴^ORCID,Chow Brian Y.¹²³⁴^ORCID

Affiliation:

1. Department of Bioengineering

2. University of Pennsylvania

3. Philadelphia

4. USA

Abstract

We report the construction of a single-component optogenetic Rac1 (opto-Rac1) to control actin polymerization by dynamic membrane recruitment.

Funder

National Institute of Mental Health

National Institute on Drug Abuse

Paul and Daisy Soros Fellowships for New Americans

National Institute of Neurological Disorders and Stroke

Division of Molecular and Cellular Biosciences

W. W. Smith Charitable Trust

National Institute of General Medical Sciences

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry

Link

Reference54 articles.

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