Effect of Ling-Gui-Zhu-Gan decoction major components on the plasma protein binding of metoprolol using UPLC analysis coupled with ultrafiltration-Reference-Cited by-同舟云学术

Effect of Ling-Gui-Zhu-Gan decoction major components on the plasma protein binding of metoprolol using UPLC analysis coupled with ultrafiltration

Published:2018 Issue:63 Volume:8 Page:35981-35988
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhou Peng¹²³⁴⁵^ORCID,Huang Jinling¹²³⁴⁵,Ding Wanxue¹²³⁴⁵

Affiliation:

1. Department of Integrated Traditional Chinese and Western Medicine

2. Anhui University of Chinese Medicine

3. Hefei 230012

4. People's Republic of China

5. Research Institute of Integrated Traditional Chinese and Western Medicine

Abstract

Using traditional Chinese medicine formula Ling-Gui-Zhu-Gan decoction (LGZGD) plus selective β₁-adrenergic receptor inhibitor metoprolol to treat arrhythmia of coronary heart disease can significantly improve efficiency with no adverse reactions.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA07153E

Reference35 articles.

1. Protective effect of metoprolol on arrhythmia and heart rate variability in healthy people with 24 hours of sleep deprivation

2. Bisoprolol compared with carvedilol and metoprolol succinate in the treatment of patients with chronic heart failure

3. Effect of Beta-Blockade on Mortality in Patients With Heart Failure: A Meta-Analysis of Randomized Clinical Trials 11All editorial decisions for this article, including selection of referees, were made by a Guest Editor. This policy applies to all articles with authors from the University of California San Francisco.

4. Characterization of plasma protein binding dissociation with online SPE-HPLC

5. Drug–protein binding: a critical review of analytical tools

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