Micro-dissected tumor tissues on chip: an ex vivo method for drug testing and personalized therapy-Reference-Cited by-同舟云学术

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Micro-dissected tumor tissues on chip: an ex vivo method for drug testing and personalized therapy

Published:2016 Issue:2 Volume:16 Page:312-325
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Astolfi M.¹²³⁴⁵,Péant B.⁵³⁴,Lateef M. A.⁵³⁴,Rousset N.⁶²³⁴,Kendall-Dupont J.⁵³⁴,Carmona E.⁵³⁴,Monet F.⁶²³⁴,Saad F.⁵³⁴⁷⁸,Provencher D.⁵³⁴⁹¹⁰,Mes-Masson A.-M.⁵³⁴¹¹⁸,Gervais T.⁶²³⁴¹

Affiliation:

1. Institute of Biomedical Engineering

2. Polytechnique Montréal

3. Montreal

4. Canada

5. Institut du cancer de Montréal and Centre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM)

6. Department of Engineering Physics

7. Department of Surgery

8. Faculty of Medicine

9. Division of Gynecologic Oncology

10. Department of Obstetrics-Gynecology

11. Department of Medicine

Abstract

Micro-dissected tumor tissues (MDTs) are maintained alive on chip for several days and show promising results for personalized medicine applications.

Funder

Prostate Cancer Canada

Canadian Cancer Society Research Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2016/LC/C5LC01108F

Reference55 articles.

1. Clinical development success rates for investigational drugs

2. Raise standards for preclinical cancer research

3. Drug development and clinical trials—the path to an approved cancer drug

4. Capturing complex 3D tissue physiology in vitro

5. The third dimension bridges the gap between cell culture and live tissue

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