A general synthesis of arylindoles and (1-arylvinyl)carbazoles via a one-pot reaction from N-tosylhydrazones and 2-nitro-haloarenes and their potential application to colon cancer-Reference-Cited by-同舟云学术

A general synthesis of arylindoles and (1-arylvinyl)carbazoles via a one-pot reaction from N-tosylhydrazones and 2-nitro-haloarenes and their potential application to colon cancer

Published:2016 Issue:88 Volume:52 Page:13027-13030
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Bzeih Tourin¹²³⁴⁵,Naret Timothée¹²³⁴⁵,Hachem Ali⁶⁷⁸⁹¹⁰,Jaber Nada⁶⁷⁸⁹¹⁰,Khalaf Ali⁶⁷⁸⁹¹⁰,Bignon Jerome¹¹¹²¹³¹⁴¹⁵,Brion Jean-Daniel¹²³⁴⁵,Alami Mouad¹²³⁴⁵,Hamze Abdallah¹²³⁴⁵^ORCID

Affiliation:

1. BioCIS

2. Equipe Labellisée Ligue Contre le Cancer

3. Univ. Paris-Sud

4. CNRS

5. University Paris-Saclay

6. Laboratory for Medicinal Chemistry and Natural Products

7. Lebanese University

8. Faculty of Sciences (1) and PRASE-EDST

9. Hadath

10. Lebanon

11. Institut de Chimie des Substances Naturelles

12. UPR 2301

13. CNRS avenue de la terrasse

14. F-91198 Gif sur Yvette

15. France

Abstract

A synthesis of aryl-indoles, and carbazoles from a one-pot sequence involving the coupling of hydrazones with nitro-haloarenes has been developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC07666A

Reference42 articles.

1. Microtubule-binding agents: a dynamic field of cancer therapeutics

2. Combretastatins: More Than Just Vascular Targeting Agents?

3. Vascular Disrupting Agents: A Novel Mechanism of Action in the Battle Against Non-Small Cell Lung Cancer

4. Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo

5. The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures

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