Tricyclic analogues of epidithiodioxopiperazine alkaloids with promising in vitro and in vivo antitumor activity-Reference-Cited by-同舟云学术

Tricyclic analogues of epidithiodioxopiperazine alkaloids with promising in vitro and in vivo antitumor activity

Published:2015 Issue:8 Volume:6 Page:4451-4457
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Baumann Marcus¹²³⁴⁵,Dieskau André P.¹²³⁴⁵,Loertscher Brad M.¹²³⁴⁵,Walton Mary C.¹²³⁴⁵,Nam Sangkil⁶⁷⁸⁵,Xie Jun⁶⁷⁸⁵,Horne David⁶⁷⁸⁵,Overman Larry E.¹²³⁴⁵

Affiliation:

1. Department of Chemistry

2. 1102 Natural Sciences II

3. University of California

4. Irvine

5. USA

6. Department of Molecular Medicine

7. Beckman Research Institute of City Hope Comprehensive Cancer Center

8. Duarte

Abstract

A short synthesis of 1,4-dioxohexahydro-6H-3,8a-epidithiopyrrolo[1,2-a]pyrazines will enable future mechanistic and translational studies of these structurally novel and promising clinical antitumor candidates.

Funder

National Science Foundation

German Academic Exchange Service London Office

National Cancer Institute

National Institute of General Medical Sciences

Alexander von Humboldt Foundation

German Academic Exchange Service

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry