Urinary enterolignans and enterolignan-predicting microbial species are favourably associated with liver fat and other obesity markers

Author:

Mo Yufeng1234,Li Yamin1,Liang Shaoxian1,Wang Wuqi1,Zhang Honghua1,Zhao Jiajia1,Xu Mengting1,Zhang Xiaoyu5,Cao Hongjuan6,Xie Shaoyu6,Lv Yaning7,Wu Yaqin7,Zhang Zhuang1,Yang Wanshui1234ORCID

Affiliation:

1. Department of Nutrition, Center for Big Data and Population Health of IHM, School of Public Health, Anhui Medical University, Hefei, Anhui, China

2. Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), Ministry of Education of the People's Republic of China, Anhui, China

3. NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui, China

4. Anhui Provincial Key Laboratory of Population Health and Aristogenics/Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, Anhui Medical University, Hefei, Anhui, China

5. Department of Physical Examination Center, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China

6. Department of Chronic Non-communicable Diseases Prevention and Control, Lu'an Municipal Center for Disease Control and Prevention, Lu'an, Anhui, China

7. Technology Center of Hefei Customs, and Anhui Province Key Laboratory of Analysis and Detection for Food Safety, Hefei, Anhui, China

Abstract

Plant-derived lignans may protect against obesity, while their bioactivity needs gut microbial conversion to enterolignans.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Anhui Medical University

Publisher

Royal Society of Chemistry (RSC)

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