Effects of core titanium crystal dimension and crystal phase on ROS generation and tumour accumulation of transferrin coated titanium dioxide nanoaggregates

Author:

Lane Daniel D.12345,Black Kvar C. L.12345,Raliya Ramesh67345ORCID,Reed Nathan67345,Kotagiri Nalinikanth12345,Gilson Rebecca12345,Tang Rui12345,Biswas Pratim67345ORCID,Achilefu Samuel12345ORCID

Affiliation:

1. Optical Radiology Laboratory

2. Department of Radiology

3. Washington University in St. Louis

4. St. Louis

5. USA

6. Aerosol and Air Quality Research Laboratory

7. Department of Energy, Environmental, and Chemical Engineering

Abstract

Radionuclide-stimulated therapy (RaST), which is enhanced by Cherenkov radiation, has enabled deep tissue stimulation of UV photosensitizers, providing a new path for cancer treatment.

Funder

National Cancer Institute

National Institute of Biomedical Imaging and Bioengineering

U.S. Department of Defense

Alvin J. Siteman Cancer Center

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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