Response of single leukemic cells to peptidase inhibitor therapy across time and dose using a microfluidic device-Reference-Cited by-同舟云学术

Response of single leukemic cells to peptidase inhibitor therapy across time and dose using a microfluidic device

Published:2014 Issue:2 Volume:6 Page:164-174
ISSN:1757-9694
Container-title:Integr. Biol.
language:en
Short-container-title:Integr. Biol.

Author:

Kovarik Michelle L.¹²³,Dickinson Alexandra J.¹²³,Roy Pourab⁴²³,Poonnen Ranjit A.¹²³,Fine Jason P.⁴²³,Allbritton Nancy L.¹²³⁵²

Affiliation:

1. Department of Chemistry, CB 3290

2. University of North Carolina

3. Chapel Hill, USA

4. Department of Biostatistics, CB 7420

5. Department of Biomedical Engineering

Abstract

Microfluidic single-cell assays of peptide degradation were performed at varying inhibitor doses, and the resulting data were analyzed by regression modeling to reveal biological effects.

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Biochemistry,Biophysics

Link

http://pubs.rsc.org/en/content/articlepdf/2014/IB/C3IB40249E

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1. Hallmarks of Cancer: The Next Generation

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