Capturing the spatial and temporal dynamics of tumor stroma for on-chip optimization of microenvironmental targeting nanomedicine-Reference-Cited by-同舟云学术

Capturing the spatial and temporal dynamics of tumor stroma for on-chip optimization of microenvironmental targeting nanomedicine

Published:2023 Issue:1 Volume:23 Page:25-43
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Imparato Giorgia¹,Urciuolo Francesco²,Mazio Claudia¹,Netti Paolo A.¹²^ORCID

Affiliation:

1. Center for Advanced Biomaterials for Health Care@CRIB Istituto Italiano di Tecnologia, Largo Barsanti e Matteucci n. 53, 80125 Napoli, Italy

2. Department of Chemical, Materials and Industrial Production Engineering (DICMAPI) and Interdisciplinary Research Centre on Biomaterials (CRIB), University of Napoli Federico II, P.le Tecchio 80, 80125 Napoli, Italy

Abstract

Reliable tumor-on-chip platforms for nanomedicine testing need to capture the spatiotemporal heterogeneity of tumors by hosting advanced 3D bioengineered tissues able reproduce the complexity of tumor microenvironment.

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D2LC00611A

Reference130 articles.

1. Tumor Microenvironment: A New Treatment Target for Cancer

2. Harnessing Extracellular Matrix Biology for Tumor Drug Delivery

3. The Current Landscape of 3D In Vitro Tumor Models: What Cancer Hallmarks Are Accessible for Drug Discovery?

4. Nanomedicine and tumor heterogeneity: Concept and complex reality

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