Metal-free stereoselective addition of propiolic acids to ynamides: a concise synthetic route to highly substituted enediyne/dienyne-(E)-N,O-acetals

Author:

Prasad Rangu1ORCID,Kanikarapu Suresh1ORCID,Dutta Shubham1ORCID,Vangara Srinivas1,Sahoo Akhila K.1ORCID

Affiliation:

1. School of Chemistry, University of Hyderabad, Hyderabad, India

Abstract

A straightforward and sustainable approach for the 1,2-addition of propiolic acids to ynamide has led to bench-stable sp2 (E)-enol-enamides of enediynes and dienynes.

Funder

Science and Engineering Research Board

Council of Scientific and Industrial Research, India

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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