Revisiting a physiologically based pharmacokinetic model for cocaine with a forensic scope-Reference-Cited by-同舟云学术

Revisiting a physiologically based pharmacokinetic model for cocaine with a forensic scope

Published:2019 Issue:3 Volume:8 Page:432-446
ISSN:2045-452X
Container-title:Toxicology Research
language:en
Short-container-title:Toxicol. Res.

Author:

Bravo-Gómez María Elena¹²³⁴⁵^ORCID,Camacho-García Laura Nayeli⁶³⁴⁵,Castillo-Alanís Luz Alejandra¹²³⁴⁵^ORCID,Mendoza-Meléndez Miguel Ángel⁷⁸⁴⁵^ORCID,Quijano-Mateos Alejandra¹²³⁴⁵^ORCID

Affiliation:

1. Forensic Science Department

2. School of Medicine

3. National Autonomous University of Mexico

4. Mexico City

5. Mexico

6. School of Chemistry

7. Research and Advanced Studies Centre

8. Politechnical National Institute (CINVESTAV-IPN). Av. Instituto Politécnico Nacional 2508

Abstract

A whole-body permeability-rate-limited physiologically based pharmacokinetic (PBPK) model for cocaine was developed with the aim to predict the concentration–time profiles of the drug in blood and different tissues in humans.

Funder

Consejo Nacional de Ciencia y Tecnología

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://pubs.rsc.org/en/content/articlepdf/2019/TX/C8TX00309B

Reference70 articles.

1. Physiologically based pharmacokinetics (PBPK)

2. PBPK modeling and simulation in drug research and development

3. A review of the applications of physiologically based pharmacokinetic modeling

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Quetiapine-Related Deaths: In Search of a Surrogate Endpoint;Toxics;2024-01-03

2. In Silico Prediction of Oral Drug Absorption;Oral Bioavailability and Drug Delivery;2023-10-10

3. An Overview of Physiologically-Based Pharmacokinetic Models for Forensic Science;Toxics;2023-01-28